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Articles

Title: Does the Helicobacter pylori infection occur in the gastric corpus after eradication with triple therapy?

Author:
Elżbieta Poniewierka, Grażyna Gościniak, Marta Rzeszutko
Type:
Original articles
Language:
EN
Journal:
Polish Gastroenterology
Year:
2003
Volume:
10
Number:
5
Start page:
395
Final page:
398
ISSN:
1232-9886
Keywords:
Helicobacter pylori, gastritis, eradication
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Introduction: The mechanisms of H.p.-induced gastric mucosa damage are still not well known, as well as the safety and effects of long-term therapy with PPIs. The aim of the study: The authors have made an effort to study whether it comes to the transmission of Helicobacter pylori (H.p.) infection and howit influences the mucosa of this region. Material and methods: For this purpose 63 patients underwent preliminary endoscopic examination of upper part of alimentary tract. During the gastroscopy biopsy specimens were collected for the histopathological examination (towards H.p.). Patients with confirmed H.p. infection underwent the eradication therapy. Gastroscopy was repeated 3-6 months after the medication. Results: We found out comparable intensification degree of inflammatory changes in corpus and pyloric part of stomach. Patients with H.p. infection located in the corpus have concomitant infection ofthe pyloric part. Helicobacter pylori has been cultured in the prepyloric part, in the inflammation part and in the gastric corpus in about 40% of the examination. The urease test has shown the presence of bacteria after the treat-ment only in 12% cases.