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Articles

Title: Application of tea tree oil and its preparations in combined treatment of dermatomycoses

Author:
Jak-Kristan W. Klimmek, Roman Nowicki, Kornelia Szendzielorz, Mariola Kunicka, Remigius Rosentrit, Grzegorz Honisz, Wojciech Król
Type:
Original articles
Language:
PL
Journal:
Medical Mycology
Year:
2002
Volume:
9
Number:
2
Start page:
93
Final page:
96
ISSN:
1232-986X
Keywords:
Tea Tree Oil, dermatomycoses, combined treatment
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Objectiues: Combined therapy is known method used to overcome the shortcoming of chemotherapeutics including toxicity, because joint administra-tion with another drug can make it possible to reduce the dose and increase the therapeutic effect. The aim of study: The aim of the study was to asses the effectiveness of treatment of mycoses using Tea Tree Oil and its preparations in combination with routinely used antimycotic drugs. Materials and methods: The studied group consisted of 67 patients with dermatomycoses. Diagnostics was carried out using solid Sabouraud medium (Sabouraud Gentamicin Chloramphenicol agar and Sabouraud Chloramphenicol Actidione agar). Two groups of preparations were used in the treatment: antifungal drugs - Lamisil (Terbinafine) or Fluconazole, and Tea Tree Oil and its preparations. The patients were divided into two groups treated according to the following schedules: Group I - 1 tablet of the antifungal drug daily (24 patients - fluconazole, 10 patients - Lamisil); Group II - 1 tablet of the antifungal drug daily (23 patients - fluconazole, 10 patients - Lamisil) plus Tea Tree Oil and its preparations. The preparations were used twice daily: spray and powder in the morning and 100% oil and antiseptic cream in the evening. Result and conclusions: The effectiveness of treatment was increased by adopting the combination therapy schedule from 56 to 88%. Tea Tree Oil and its preparations markedly support the oral treatment of dermatomycoses.