Title: Dental caries-associated risk factors and type 1 diabetes mellitus
- Norma Sampaio, Sandra Mello, Cresio Alves
- Review articles
- Pediatric Endocrinology, Diabetes and Metabolism
- Start page:
- Final page:
- caries, type 1 diabetes mellitus, salivary flow, dental plaque
Introduction: Type 1 diabetes mellitus (T1DM) is associated with various oral complications. However
there is no consensus regarding the association of T1DM and caries.
Aim of the study: Critical revision of dental caries-associated risk factors and type 1 diabetes mellitus.
Materials and methods: Search of the MEDLINE and LILACS databases from 2000 to 2010, using,
in different combination, the key words "dental caries", "diabetes mellitus" and "type 1 diabetes mellitus".
Results: The association between T1DM and dental caries remains controversial. Although some
studies demonstrate a higher prevalence of caries due to the increased concentration of salivary
glucose, acidity of the oral cavity, salivary viscosity, reduced salivary flow rate, and salivary gland
dysfunction; other studies report a reduction of caries levels, probably caused by decreased sucrose
Conclusions: Although patients with uncontrolled T1DM and poor oral hygiene may present increased
prevalence of dental caries, the literature does not describe a consistent relationship between
T1DM and dental caries. Further investigations are warranted. If a true association is substantiated,
intervention studies to prevent or reduce the occurrence of caries in this population should follow.