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Articles

Title: Bosentan - based treatment of pulmonary arterial hypertension in the course of Eisenmenger's syndrome - case report

Author:
Dominika Filipiak, Ewa Szymczyk, Waldemar Rogowski, Jarosław D. Kasprzak
Type:
Case Reports
Language:
PL
Journal:
Polish Journal of Cardiology
Year:
2009
Volume:
11
Number:
3
Start page:
236
Final page:
239
ISSN:
1507-5540
Keywords:
pulmonary hypertension, Eisenmenger’s syndrome, bosentan
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Pulmonary arterial hypertension (PAH) is a rare pathology of pulmonary circulation in which the mean pulmonary artery pressure assessed by direct hemodynamic measure is >25 mmHg at rest or >30 mmHg with exercise. Eisenmenger’s syndrome is an extreme manifestation of PAH secondary to congenital heart defect. The article presents a 39-year-old female patient suffering from congenital ventricular septum defect combined with Eisenmenger’s syndrome and permanent pulmonary hypertension. The patient was included into the pulmonary treatment program and treated with bosentan. After two months of therapy, control tests indicated improved tolerance to exercise without decreased peripheral oxygen blood saturation.