Title: Gluteal skin is not an optimal biopsy site for direct immunof luorescence in diagnostics of dermatitis herpetiformis. A report of a case of dermatitis herpetiformis Cottini
- Anna Lutkowska, Paweł Pietkiewicz, Joanna Sulczyńska-Gabor, Justyna Gornowicz, Monika Bowszyc-Dmochowska, Marian Dmochowski
- Case Reports
- Clinical Dermatology
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- Final page:
- dermatitis herpetiformis, direct immunofluorescence, gluteal region
Dermatitis herpetiformis (DH) isan autoimmunebullous dermatosisconnected with gluten-sensitiveenteropathy. Direct immunofluorescence test (DIF) of nonlesional skin remainsdefinitivelaboratory test fordiagnosingthisdisease. We present here a case of DH Cottini, inwhom DIF of gluteal skin was negative, but DIFof perilesional knee skin revealed IgA deposits characteristic for DH. On the ground of literature data and our own experience we think that in patients suspected of having DH, in whom there were and there are no lesions on buttocks (such as in cases of DH Cottini) DIF should not be performed on gluteal skin. Still, in DH cases in whom lesions are on buttocks, gluteal skin should still be regarded as an appropriate biopsy site for performing DIF.