Title: Assessment of the antral nodularity as the manifestation of Helicobacter pylori infection in children
- Beata Korus, Piotr Albrecht, Jacek Bujko, Jan Wyhowski
- Contemporary Pediatrics, Gastroenterology, Hepatology and Child Feeding
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- Helicobacter pylori, nodular gastritis, urease test, children
Introduction: Antral nodularity is a unique and frequent endoscopic feature of antral gastritis caused by Helicobacter pylori (H. pylori) infection in children. The severity of antral nodularity varies between patients from considerable nodularity to vast, easy visible "paving sto-nes".
Aim of study: Estimation of the frequency of H. pylori infection according to severity of antral nodularity. Assessment of correlations between severity of antral nodularity time and positive outcome of urease test and between endoscopic evaluation and grade of histopato-logically assessed antral gastritis.
Material and methods: 120 children (6-18 years) with endoscopically assesed antral nodularity were included into the study. Patients were divided according to the severity of nodularity into 3 groups: I - inconsiderable nodularity, II - apparent nodularity, III - vast nodularity. H. pylori infection was preliminarily diagnosed on the basis of two methods: macroscopic picture of antral mucosa (nodularity) and positive urease test.
Results: 98% (41/42) of children with vast antral nodularity, 90% (52/58) of patients with apparent nodularity and 65% (13/20) of children with considerable nodularity were found infected with H. pylori. In all of them antral gastritis was found. Prompt positive test determination was found in 59% of patients from the lll rd group and only in 31% of children from the 1st group.
Conclusions: Antral nodularity is a reliable marker of H. pylori infection in children. There is a good correlation between severity of antral nodularity and promptness of positive outcome in urease test.