Title: Review: rotavirus infection complications
- Hanna Szajewska, Anna Chmielewska
- Contemporary Pediatrics, Gastroenterology, Hepatology and Child Feeding
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- rotavirus, complications, infection
This systematic review serves as a reminder of both typical and unusual complications of rotavirus (RV) infection. Medical subject headings and free-language terms were used to search MEDLINE and The Cochrane Library (both up to January 2008) for relevant trials. RV infection is usually a self-limiting condition. However, complications may occur. The clinical consequences include dehydration, metabolic acidosis, and electrolyte disturbances. If left untreated, this may result in hypovolemic shock and death. Although rarely, rotavirus has been asso-ciated with complications within the gastrointestinal tract (e.g. gastroparesis, hypertransaminazemia, hepatitis), or other syndromes, inc-luding neurologie symptoms, respiratory infection, secondary bacteraemia. However, a rotavirus etiology sometimes has not been proven. It has been speculated that RV may also play role in the pathogenesis of diabetes type 1 and coeliac disease.