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Articles

Title: Low serum cholesterol levels in hospitalised chiidren

Author:
Piotr Socha, Grzegorz Oracz, Krzysztof Cieślik, Paulina Kremky, Małgorzata Rogaszewska, Ewa Pronicka, Jerzy Socha
Language:
PL
Journal:
Contemporary Pediatrics, Gastroenterology, Hepatology and Child Feeding
Year:
1999
Volume:
1
Number:
2-3
Start page:
161
Final page:
164
ISSN:
1507-5532
Keywords:
hypocholesterolemia, malnutrition, Smith-Lemli-Opitz syndrome
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Hypercholesterolemia is an importantclinical problem in adults and chiidren. However, low cholesterol levels, which are the matter of far less concern, also seem to be of great importance. The aim of our study was to investigate possible reasons leading to decreased serum cholesterol level in hospitalised chiidren. We se-lected 34 chiidren aged 1 month to 11 years (mean 1.8 years) from 200 chiidren whose cholesterol results were randomly obtained from the lab. We evaluated clinical diagnoses, methods of nutrition, nutritional status, serum cholesterol levels and other biochemical parameters. We found very low cholesterol levels in 19 chiidren and low levels in 15 chiidren (altogether 34 chiidren aged 1 month-11 years). At the same time severe mal-nutrition was observed in 17 chiidren, moderate malnutrition in 8 chiidren. 5 chiidren had normal nutritional status. There were different reasons for hospitalisation: short bowel syndrome (8), Smith-Lemli-Opitz syn-drome (5), liver diseases (5), metabolic diseases (5) and other. 7 patients were on parenteral nutrition, 4 patients had special diets (gluten-free, lactose-free, Iowtyrosine-fenylalanine), 4 patients were on high-cholesterol diet. In the course of hospitalisation serum cholesterol levels in the chiidren raised slightly how-ever standard deviation scores did not change significantly. In hospitalised chiidren hypocholesterolemia seems to occur as a result of malnutrition which accompanies chronic diseases. It is also important to consider Smith-Lemli-Opitz syndrome among patients with low cholesterol levels.