Title: Nutritional support of infants and children. Supply and metabolism of lipids
- Berthold Koletzko, Piotr Socha, Hans Demmelmair, Thorsten Sauerwald
- Contemporary Pediatrics, Gastroenterology, Hepatology and Child Feeding
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- linoleic acid, long-chain polyunsaturated fatty acid, medium chain triacylglycerides, ro-3 fatty acids, vitamin E
The amount and naturę of fats supplied with the diet and their metabolic fate in the organism are of major importance for growth, body composition, development and long-term health of children. Fats are the pre-dominant source of energy in early childhood and supply essential lipid soluble vitamins and polyunsaturated fatty acids that are required in relatively high amounts during early growth. Lipids play important structural roles and modulate membranę composition and functions as well as the development of nervous system functions. Some long-chain polyunsaturated fatty acids also serve as precursors for bioactive lipid mediators, including prostaglandins, thromboxanes, and leukotrienes that are powerful regulators of numerous cell functions such as thrombocyte aggregation, inflammatory reactions and immune functions. Aspects of the biochemistry and physiology of fats and their implications for lipoprotein metabolism, energy balance and the lipid supply during early childhood are discussed here.